Kallidinogenase
Source: Porcine (Bovine) PancreasGeneraldescription
PancreaticKallidinogenase (Kallikrein) is a proteolytic enzyme. Composed of 18 kinds ofamino acids and 4 kinds of sugar, Mr is 26800 daltons. It can liberate Kallidin fromKininogen . Kallidin then dilates vascular smooth muscle tissue andthus reduces blood pressure.
Application
--In clinical, used for treatment ofMicrocirculation disorders, such as gastrosia induced by diabetes, peripheralneuropathy, retinopathy, ocular fundus disease and ischemic cerebrovasculardisease, can also be used as adjuvant therapy of essential hypertension etc.
Specification
| Item | Specification | Standard |
| Apperance | white or light yellow powder | CP 2010 |
| Identification | Conform | CP2010 |
| PH | 5.5-7.5 | CP2010 |
| Fat | ≤5.0mg/g | CP2010 |
| Absorbance | A280nm≤ 0.2 | CP2010 |
| Residue on ignition | ≤3.0% | CP2010 |
| Loss on drying | ≤5.0% | CP2010 |
| Purity | ≥75% | CP2010 |
| Assay | Not less than 300 units/mg, calculated on the dried basis. | CP2010 |
Sealed, Dark, Preserved in a cool and dry place.